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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653ff4e9e48a547d15c33a525fbf9069fd6ea1b97cb8f7263691dcd1fc030ce5' 
  AND token = '2/oxDFy6YlgtYzElf1iz9bp7PfgpbYfs4itJOMQGbt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}