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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6191620a73595667689f6e86515545828e9d8517f292709b41c772aa9dd59e09' 
  AND token = 'umN6h6vWOHZvyAlVVer7fqeb5eBwEP8/GpaVAz2O3ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}