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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a183841abb483190d91a6efa63b23688176f73e8cc5b9be4e7ae278b926eb8' 
  AND token = '4EVOjHiA+IrbPYzFsVjSB1RusFIfaSWHdhxRI96xt60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}