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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9405a07bdddae5b94aa0c33b43cab75a0d67f3c64c6638d21c29533ea52d9e41' 
  AND token = 'cdW9tmW6KMcGGz5d0vX2zdel3TSzsZXBuzR+Xb2hiXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}