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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3767fe621fd3cf02f4d338448b10a7bbee161e73bc349bcee9b68c64e4f4fd5f' 
  AND token = 'urgm7vmA86EZFg1YwPT71vuR257HnjjUK6t0aJ7Xhm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}