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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f220d5088e04c02180805fb66eff41175bc74e5b0cb134e04d720c5a8eced1c9' 
  AND token = 'WIa4lS3qnHvy2ICCSMhGCPuSs6bhJh+EZDTz/4GDY40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}