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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de33b943e6fadce0d213e65d6137b6fde5a6c8be7c7d2dbc5dd099019969accf' 
  AND token = 'puyoKJWKiN5oU5eC30/QJ7XA/nXUZxKPRgLySEuKeb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}