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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd11649e23d16ba48f6f397b1a8a1c3f33a978f2b505f9bd838fb75cf5ed53b2' 
  AND token = '28vcnEOkAtP7zDd0xrbxukZ2uQdfH3PpDAL+rubnOw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}