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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a258acb5a3c675c1d33a8b5efc1cb359478055ad6affe5699211d06765be1e5b' 
  AND token = 'CUEci3ULiTPy1aNGPQ8UkZGZ76PyL7D4Adb1hzkQKT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}