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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '618d26b363869f19f15814a6455c12d29f8c99a376cb1040c2636fe05c7d3fa2' 
  AND token = 'CFVZc02gnNbSJULFEHRuRwPuZYN7IYPXXs0htfXC1Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}