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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522b67ddf12b77a2241548e950c3a2dfdc2bcab01aaabb8c1494f17e5aa48687' 
  AND token = 'qpwg+i8+ln6HK4n72QMcf4L/6q1mqYeD1dikdIdWBWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}