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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0287e8d2a181cac27da732f5d1bcfaad1730255723d6df4aa0ba9d862eec8c0f' 
  AND token = '5qU8o9PA5s3R6+xTnizYwsZT5kXk4ym+uwr0+jU+OI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}