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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00c920b5848ee3a91b4abd68e1f88b5de1b9822b1c17609b342e2994c64cc83' 
  AND token = 'FkQWwIogPvaCLNF6wfUhl4tVdkyPCVDIGDgZcbOG6gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}