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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65ff91d3d1f008b731b4b24de7bf7331ab1b80ac0c815e745383f121f6eb01f' 
  AND token = 'crzh4yZ1mhxYAeQNbfZ2Qm5ytjRikdlzLhHrTws6wYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}