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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea731b35786df3dcde0511e24bf0e9c8481b8f931ce87e85a7fddb8a96ed1e37' 
  AND token = 'rwO3DMpPtS9MrBR8IO6YYd2NylStQHm0Gjtj0ei3MjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}