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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600106c3b3d19b704a39fab28237fe61b6cee2453f11de3579e168455d94d7de' 
  AND token = 'dwWt11/UwQomY5ro2zZElOkO1cCvW/TIYvlQYm9o1OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}