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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48058b9972b80705d2d2d1d12873cad4b788fccf555ed31d3d81c5719f644c0' 
  AND token = 'itMCOlYb5MjxlQtq1osunerIjfWLvbSIRlkyb43fMO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}