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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d246e9304bdb22a1082b39445069d87b03a89a5013cf05fda93be5cc2d26a35' 
  AND token = 'AlVYHG5X5eQmRaoFlTbrbUZyUfJ7QE+z4duyPZvuWe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}