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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045ccf56ba899182aedee6e21a25c7ce5d2148d570e851e2e7c6988fb699ce43' 
  AND token = 'Hd1dP73PfdRdwxqMTt21N3HLy3B3GfvqV41qjnS7H24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}