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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f623f773951b066bdcb0b38fb15d3ecec2450935009e7eef149d616335c84af' 
  AND token = 'lFu6SFPdDpbnnHi7wb2rYrPeVI5CUxzZV8nLXSo4OD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}