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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6aaa19b990463ebadbea1b45a1d5d988dd89ecf0d39d51c38843f5c1ac5b648' 
  AND token = 'pOHR5C4+Mx523T76gDm7sxBQOYxWWzx163mDjVZLGuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}