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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c0d7335e26c7e3081cef151de5ef32dc3127ff04ba17f9538ae0ccc17d0157' 
  AND token = 'gwitD3FYOreae0KTicSwMQi0GNJbXdxTaYFjzjqOJwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}