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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce313e335465aede0fda10a1100a43fdf1889727c15d801ddffd90aff2646400' 
  AND token = 'DxWrecF4o8jkIh0SgfY+kyUbOOC2zPaWqSVKvlx7Hgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}