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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e64a74ac5a6d7a44b569cae49dcdc0d11d1c19c7c6dceebb7daa18bd292d13' 
  AND token = 'u1oX2l/e8yaPGzqWqVIhZg3EIV+caWo/F+xOLh9pOIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}