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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb06e53bdb9d6de4969fc374987787decef0cf0813be6be78eb6e9dce927b83' 
  AND token = 'ct6dqC+lVU6p9aGPq3Osemfnvf8DhqmsBynxui4dT4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}