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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5018a804be8809c093b2386ef1345aa103735d13e914b95d3157270f10f68857' 
  AND token = 'SzZpC4TeUHMFHqG4bj4xeXSAqAemovyJmkAfn7XntjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}