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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce59efc8e2e11f5cc1946a0e101bfc948f0d6707a95cb7cfd4b68590a356d486' 
  AND token = 'FX5mHVp7s97zegLkXvypi8GlvyAup8tmF8xuchET9bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}