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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78dce1a749bdd0f9e1eccfbc1fe8e4f431e44019b8228f1481cafbfa04a4a71b' 
  AND token = 'K4CDPZ5eE9IyfgI3dBewS8gjUb2dzc6dTiTDDrr2s4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}