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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf36231bdaff69001d6469fb1646ec904b46865c569505e906e62ef76baf1de4' 
  AND token = 'w2e/eIO5NoMcgAoSqPQ2yVQwoRjrCqaMcITL5Y2JUWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}