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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f3a608e82e559ba266aa67bfdb8a2639f74885cd9fbf0a9ebc65bdfdcef5be' 
  AND token = 'Yj+sPQl6c5WE4PSu4RHYmmB7TXvLU1jxNZ36S2i8UN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}