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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7e28b2c1a76691cbeee91113e716058ab0ce5d146ad6ba4724b6de4799a3fa' 
  AND token = 'MMlIaOSXv4XJ7id6cjmgBTmD8YHjpmKsCwpVcn0M0Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}