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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0ac95111bad1a049cc0e630e3afafb4e9d8eee8f875c3be9f37e43c6171cae' 
  AND token = '9zGC0xRwxs1T1NpxKmoiVxLJaTgKtzsNW80x29Gq3cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}