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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5489e07d831858e90114d2ecc88032a39e33fd86828f98e9a40845be21e1fe1' 
  AND token = '9Zpx4ggt6Dy/IgjdspE/E8J5rVXTT732mTCcXjbI4U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}