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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d045f37b4679704870837df52179280647127a598b761907c970aed2b4bc054' 
  AND token = 'rhClPTP1Q7vUq6xCdTQUh0M6tLDGpiuJ6IeYZ5Gx9LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}