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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eaee4c10d898e38c4c0d3ba0144f5ee609f46a4f9428b40d3c931f23a2da378' 
  AND token = 'YPZA6SyV7eg0LIgae+vAV/mj+NouOIq/fnk0wy+qcHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}