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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6b28c05a4af724b9a42c20812de9d7ce1a3516f7d7614b2e08cf0fc11b5e3c' 
  AND token = 'GF/jJvBQorju5n4aymL3I0bW6YgajSsRVJufgBN1oAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}