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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57dfd6c81b1bd2e49f6e0dbdbfdcd244013d7c94ca3e8bc0b81afd0f233dd6e5' 
  AND token = '1AGb/WlQggZz+/RMOnXXVgcjNNxHboPOpRhtRCcad4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}