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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cde2e8e24b2b7dc6e629fea6d46efa5a58267d81a205e89f52adc7a1c150beb' 
  AND token = 'CKHMdc24CmRIpi7g+nLhrc2AxF0g8cokhIOal94ZftA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}