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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59deb2869fc6794b9d09d5aa7cd9b7e377a868c6306e6bfa724fd6f504b60cc4' 
  AND token = 'SQXQuZ30iq1YKwKaDVD8DLWBtAPouJ9e5aWC3dsC6Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}