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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4321112f43a5b4727c3b29587f4726509757469836d03ca61d1f4d7796bb97de' 
  AND token = '3A/Eq8StS4iH8WI3gcae0DNLVHHHlvNcMKVujFz4U9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}