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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211d979398c7b7dbc01999121cfa8a1c21bd748c83fe18d2cc57504c638b71c4' 
  AND token = 'SULGb/aCcndtoG/x0bUp32NegjiR8tKGL73OlgwJW/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}