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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d178f335374748dc12a448b7ff7459763000eaa5a0e0bb8eb34109301a7782' 
  AND token = 'RdALPCh7xX31ufHbSk1chcnhC2LPL3W6vc8DwZgf260=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}