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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431bd12bd3b61b34ee23080395eee5d8b699ebe60ae263f5f83316ae088acfcd' 
  AND token = 'Cksnv2G9jQLBncjF4UaN0qO7MlJPa1m35F4gY7eSrSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}