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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cfeb570cbec52a2f34840dbe00aba49e484710d48d0643863d0e23b71626d9f' 
  AND token = 'rKMIBtYcjtvl69tdVC0OWW0AEHGmt3gUbdbWjzLyhdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}