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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80093c4b1f998c69d0404f94451e6bb1b3af4fb6071a3ea226264609633b6ac0' 
  AND token = 'DVVpw2PkjUZElpkmyFV7sRPMz37l8pj/YuNlGwZmEOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}