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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2572c48ecc0d70524594d6a17496f76b436dcad76792c49de0fbb66aeb2adfba' 
  AND token = '8I6/0E2Zq+IboF5Q+eFUzRVxIKPvnD2I65uRRx/gCQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}