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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b104a54d3f9536e6e5f33db4d8ecb0116beed374e311cdfb78844bf643b47c57' 
  AND token = '3H3WZCpt4Wz9xFNZtiPbx4M1tlVaOtQ0rPs7m6/0Vik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}