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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46045ac27d81e0a0ddde2dd95454f867027da7c23678aa6a6c42b2ad7beba9a6' 
  AND token = 'TPr9TNPtfwoIY7A4AZc/bNnx7Qhlu3gzcnfpyATwjXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}