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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e58ea44d10f5eb1ccb71672b9aae188b35d278ac53a7b620a9263194abfab288' 
  AND token = 'Eopct2tSr/HOtQ/QqnA6BKY4vhKalZMURmzzrGe8rRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}