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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a066a87df460f847281fee3839b3d5ab6c6a05f76aaf99e1074a190067fd56' 
  AND token = 'f16R3zIM2Stlxza5HMCOITS+L3ThErPz+8Mm/ZWW3mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}